With eSubmissions now a reality for the Life Sciences industry, you have probably been defining and investing in your electronic submission requirements. But just as important are the associated publishing requirements that support and streamline the actual eSubmission compilation process.

Any eSubmission solution will benefit from having compliant and submission-ready source content (PDF), and that’s where a-Pulse can help.

WHAT a-Pulse CAN DO FOR YOU

Automated PDF Utilities for Life Sciences, or a-Pulse™, is a collection of Adobe^® Acrobat^® plug-ins that automates the publishing and QA/QC of PDF documents intended for Electronic Regulatory Submissions.

Developed specifically for the Life Sciences industry, a-Pulse provides PDF publishing functionalities and navigational tools not available in Acrobat^®, making the PDF publishing process easier, quicker and more accurate.

Unlike any other offering or approach, a-Pulse is not a “tool-box” but an actual solution that automates the process of bookmarking, hyperlinking, formatting and publishing submission ready documents, based on multiple agency requirements for PDF in any type of eSubmission.

a-Pulse IN-DEPTH

Specifically designed to help authors, publishers and compilers reduce the time taken for the PDF publishing process, and with navigational tools for reviewers that facilitate the process of working with multiple documents, a-Pulse is the only solution that will meet
all of your publishing requirements:

• eSub Compliance Tools
  • PDF Security: Display the security information for PDF files
  • Optimize PDF: Verify and modify the PDF optimization information
    
• Links Tools
  • Cross Linker: Automate the internal and external linking process by selecting keywords. Cross Linker searches for the keywords and creates links around them to the specified destination
  • Delete: Delete hypertext links with a single mouse click
  • Touch-up: Automatically modify hypertext link attributes, including text color
    
• Verify/Fix Tools
  • IntelliQC: Verify and modify PDF navigation functions
  • Doc Info: Verify and modify PDF Document Information Fields
  • Font Info: Verify font information of PDF files to ensure their compliance with the regulatory agency requirements
    
• Bookmark Tools
  • Delete: Delete all bookmarks with a single mouse click
  • Clone: Create or remove bookmarks in multiple PDF documents (targets) by selecting existing bookmarks from a PDF document (source)
    
• Links and Bookmarks Tools
  • TOC Linker: Create bookmarks and links for the Table of Contents (TOC) in a PDF file automatically.
  • Import: Import hypertext link and bookmark attributes from a comma delimited (CSV) file to an open PDF document
  • Export: Export hypertext link and bookmark attributes from an open PDF document to a comma delimited (CSV) file
  • Document Linker: Create external file hypertext links and bookmarks for one or more selected items
  • Change Magnification: Change magnification for all bookmarks and hypertext links
    
• PDF Tools
  • Split: Split a PDF into multiple documents by specifying the page number or bookmark level at which the file should be split. 
  • Merge: Merge multiple PDFs into one file and supports remapping bookmarks and hypertext links.
  • Supports remapping bookmarks and hypertext links in both split and merge.
    
• Review Tools - Navigational functions that enhance Adobe Acrobat. These tools can be used with one or multiple PDF documents. Use multiple document mode to navigate through all the open documents simultaneously. The features include:
  • Auto Navigation - Auto Forward, Auto Backward
  • Bookmarks - Bookmarks Expand All, Bookmarks Collapse All, Bookmarks Expand to Level 1 and Bookmarks Preferences
  • Page Navigation - Absolute/Relative (GoTo/First/Last/Next/Previous/Document Mode)

WHY USE a-Pulse?

Background:

• The current requirements for regulatory submissions specifies that all documents are to be submitted in a PDF format with specific PDF formatting specifications.
• The eSubmission preparation is a collaborative effort that includes multiple contributors. The documents created for submission may or may not follow agency requirements.
• a-Pulse is designed to help contributors and regulatory publishing personnel, assisting them in determining the compliance of various documents that will become part of an eSubmission.
• a-Pulse is designed to assist authors and publishers to automate PDF publishing process and reduce eSubmissions preparation time.

• Automated functions for consistency and reduced errors
• Batch processing for increased efficiencies
• Increased quality in the preparation of your document
• Compliant with agency requirements and industry standards
• Intuitive and easy to use for immediate return of investment